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Search term: YPR074C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TKL1
SGD link S000006278
Alternative ID YPR074C
Description Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
Synonyms YPR074C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0523 ACDHYPE

KOGs classification KOGs description
METABOLISM Transketolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g45290 GI:15225449
Arabidopsis thaliana (Ath) At3g21500 GI:11994386
Arabidopsis thaliana (Ath) At3g60750 GI:11257215
Arabidopsis thaliana (Ath) At4g15560 GI:15234642
Arabidopsis thaliana (Ath) At5g11380 GI:15239030
Caenorhabditis elegans (Cel) CE09163
(WBGene00008506)		 GI:17539652 O17759
Drosophila melanogaster (Dme) 7293904 GI:7293904
Drosophila melanogaster (Dme) 7299065 GI:7299065
Homo sapiens (Hsa) Hs4507521
(TKT)		 GI:4507521 P29401
Homo sapiens (Hsa) Hs7110727 GI:7110727
Homo sapiens (Hsa) Hs14149797 GI:14149797
Saccharomyces cerevisiae (Sce) YBR117c
(S000000321)		 GI:6319593 P33315
Saccharomyces cerevisiae (Sce) YPR074c
(S000006278)		 GI:6325331 P23254
Schizosaccharomyces pombe (Spo) SPBC2G5.05 GI:19112858 Q9URM2
Encephalitozoon cuniculi (Ecu) ECU06g0120 GI:19074262 Q8SVF0
Arabidopsis thaliana (Ath) At2g45290 GI:15225449
Arabidopsis thaliana (Ath) At3g21500 GI:11994386
Arabidopsis thaliana (Ath) At3g60750 GI:11257215
Arabidopsis thaliana (Ath) At4g15560 GI:15234642
Arabidopsis thaliana (Ath) At5g11380 GI:15239030
Caenorhabditis elegans (Cel) CE09163
(WBGene00008506)		 GI:17539652 O17759
Drosophila melanogaster (Dme) 7293904 GI:7293904
Drosophila melanogaster (Dme) 7299065 GI:7299065
Homo sapiens (Hsa) Hs4507521
(TKT)		 GI:4507521 P29401
Homo sapiens (Hsa) Hs7110727 GI:7110727
Homo sapiens (Hsa) Hs14149797 GI:14149797
Saccharomyces cerevisiae (Sce) YBR117c
(S000000321)		 GI:6319593 P33315
Saccharomyces cerevisiae (Sce) YPR074c
(S000006278)		 GI:6325331 P23254
Schizosaccharomyces pombe (Spo) SPBC2G5.05 GI:19112858 Q9URM2
Encephalitozoon cuniculi (Ecu) ECU06g0120 GI:19074262 Q8SVF0
Arabidopsis thaliana (Ath) At2g45290 GI:15225449
Arabidopsis thaliana (Ath) At3g21500 GI:11994386
Arabidopsis thaliana (Ath) At3g60750 GI:11257215
Arabidopsis thaliana (Ath) At4g15560 GI:15234642
Arabidopsis thaliana (Ath) At5g11380 GI:15239030
Caenorhabditis elegans (Cel) CE09163
(WBGene00008506)		 GI:17539652 O17759
Drosophila melanogaster (Dme) 7293904 GI:7293904
Drosophila melanogaster (Dme) 7299065 GI:7299065
Homo sapiens (Hsa) Hs4507521
(TKT)		 GI:4507521 P29401
Homo sapiens (Hsa) Hs7110727 GI:7110727
Homo sapiens (Hsa) Hs14149797 GI:14149797
Saccharomyces cerevisiae (Sce) YBR117c
(S000000321)		 GI:6319593 P33315
Saccharomyces cerevisiae (Sce) YPR074c
(S000006278)		 GI:6325331 P23254
Schizosaccharomyces pombe (Spo) SPBC2G5.05 GI:19112858 Q9URM2
Encephalitozoon cuniculi (Ecu) ECU06g0120 GI:19074262 Q8SVF0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000321
SpoSPBC2G5.05
GO:0005737 cytoplasm C
IDA
SceS000000321
ISS
SceS000006278
SpoSPBC2G5.05
GO:0005829 cytosol C
EXP
HsaTKT
IDA
SpoSPBC2G5.05
GO:0009507 chloroplast C
IDA
AthAt2g45290
At3g60750
At4g15560
GO:0009570 chloroplast stroma C
IDA
AthAt3g60750
At2g45290
GO:0009941 chloroplast envelope C
IDA
AthAt3g60750
GO:0004802 transketolase activity F
EXP
HsaTKT
IMP
SceS000006278
ISS
AthAt3g60750
At2g45290
SceS000000321
S000006278
SpoSPBC2G5.05
GO:0005515 protein binding F
IPI
HsaTKT
GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase
activity		 F
IDA
AthAt4g15560
ISS
AthAt3g21500
At5g11380
TAS
AthAt5g11380
At3g21500
GO:0002119 nematode larval development P
IMP
CelWBGene00008506
GO:0006098 pentose-phosphate shunt P
IGI
SceS000000321
IMP
SceS000006278
TAS
SceS000006278
GO:0006417 regulation of translation P
RCA
SceS000006278
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00008506
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00008506
GO:0009052 pentose-phosphate shunt, non-oxidative
branch		 P
IC
SpoSPBC2G5.05
GO:0009651 response to salt stress P
IEP
AthAt3g60750
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00008506
GO:0015995 chlorophyll biosynthetic process P
IMP
AthAt4g15560
GO:0016114 terpenoid biosynthetic process P
ISS
AthAt3g21500
At5g11380
GO:0019288 isopentenyl diphosphate biosynthetic process,
mevalonate-independent pathway		 P
TAS
AthAt4g15560
GO:0040007 growth P
IMP
CelWBGene00008506
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00008506
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000006278
GO:0046686 response to cadmium ion P
IEP
AthAt3g60750
At2g45290

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38419

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC2G5.05 GI:19112858 Q9URM2
Saccharomyces cerevisiae (Sce) TKL1
(S000006278)		 GI:6325331 P23254
Kluyveromyces lactis (Kla) TKT1_KLULA GI:50303973
Eremothecium gossypii (Ego) AGOS_ADL366W GI:45187507
Magnaporthe grisea (Mgr) MGG_02471 GI:39968757
Neurospora crassa (Ncr) NCU01328.1 GI:32412682
Arabidopsis thaliana (Ath) AT2G45290 GI:30689983
Arabidopsis thaliana (Ath) AT3G60750 GI:18411711
Oryza sativa (Osa) Os06g0133800 GI:115466224
Plasmodium falciparum (Pfa) PFF0530w GI:86170850


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC2G5.05
GO:0005737 cytoplasm C
ISS
SceS000006278
SpoSPBC2G5.05
GO:0005829 cytosol C
IDA
SpoSPBC2G5.05
GO:0009507 chloroplast C
IDA
AthAt2g45290
At3g60750
GO:0009570 chloroplast stroma C
IDA
AthAt3g60750
At2g45290
GO:0009941 chloroplast envelope C
IDA
AthAt3g60750
GO:0004802 transketolase activity F
IMP
SceS000006278
ISS
AthAt3g60750
At2g45290
SceS000006278
SpoSPBC2G5.05
GO:0006098 pentose-phosphate shunt P
IMP
SceS000006278
ISS
PfaPFF0530w
TAS
SceS000006278
GO:0006417 regulation of translation P
RCA
SceS000006278
GO:0009052 pentose-phosphate shunt, non-oxidative
branch		 P
IC
SpoSPBC2G5.05
GO:0009651 response to salt stress P
IEP
AthAt3g60750
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000006278
GO:0046686 response to cadmium ion P
IEP
AthAt3g60750
At2g45290

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_201

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8189 ENSANGP00000021969
Anopheles gambiae (Aga) aga12852 ENSANGP00000026099
Ashbya gossypii (Ago) ago1375 ADL366W
Arabidopsis thaliana (Ath) ath11751 At2g45290.1
Arabidopsis thaliana (Ath) ath17508 At3g60750.1
Caenorhabditis elegans (Cel) cel5400 F01G10.1
(CE09163;
WBGene00008506)
Candida glabrata (Cgl) cgl716 CAGL0D01298g
Cryptococcus neoformans (Cne) cne761 163.m03836
Cryptococcus neoformans (Cne) cne733 163.m04712
Cryptococcus neoformans (Cne) cne1758 164.m02151
Cryptococcus neoformans (Cne) cne1759 164.m02526
Cryptococcus neoformans (Cne) cne2893 167.m05754
Dictyostelium discoideum (Ddi) ddi3770 DDB0217422
Dictyostelium discoideum (Ddi) ddi12046 DDB0231244
Debaryomyces hansenii (Dha) dha705 DEHA0B00605g
Debaryomyces hansenii (Dha) dha4436 DEHA0F01155g
Debaryomyces hansenii (Dha) dha4583 DEHA0F04378g
Drosophila melanogaster (Dme) dme10079 CG5103-PA
(FBgn0036784)
Drosophila melanogaster (Dme) dme11545 CG8036-PB
(FBgn0037607)
Drosophila melanogaster (Dme) dme11546 CG8036-PC
(FBgn0037607)
Drosophila melanogaster (Dme) dme11547 CG8036-PD
(FBgn0037607)
Danio rerio (Dre) dre15319 ENSDARP00000017569
(tkt)		 Q6PHI8
Danio rerio (Dre) dre31050 ENSDARP00000044546
Danio rerio (Dre) dre31049 ENSDARP00000045887
(LOC557518)
Escherichia coli (Eco) eco2386 16130390
Escherichia coli (Eco) eco2835 49176286
Encephalitozoon cuniculi (Ecu) ecu1489 19074262
Takifugu rubripes (Fru) fru20904 SINFRUP00000145381
Takifugu rubripes (Fru) fru20905 SINFRUP00000145384
Takifugu rubripes (Fru) fru26072 SINFRUP00000157989
Gallus gallus (Gga) gga5168 ENSGALP00000008497
Gallus gallus (Gga) gga5167 ENSGALP00000008498
(TKT)
Homo sapiens (Hsa) hsa24806 ENSP00000280605
(TKTL2)		 Q9H0I9
Homo sapiens (Hsa) hsa22645 ENSP00000296289
(TKT)		 B3KPZ8
Kluyveromyces lactis (Kla) kla934 KLLA0B09152g
Mus musculus (Mmu) mmu26034 ENSMUSP00000002025
(MGI:1921669)		 Q9D4D4
Mus musculus (Mmu) mmu7843 ENSMUSP00000022529
(MGI:105992)		 P40142
Neurospora crassa (Ncr) ncr1287 NCU01328.2
Oryza sativa (Osa) osa5189 2347.m00156
Oryza sativa (Osa) osa14224 3006.m00143
Oryza sativa (Osa) osa19956 3385.m00173
Oryza sativa (Osa) osa66245 6780.m00125
Oryza sativa (Osa) osa84670 8276.m00148
Plasmodium falciparum (Pfa) pfa3071 PFF0530w
Rattus norvegicus (Rno) rno12319 ENSRNOP00000018987
(RGD:1304767)
Rattus norvegicus (Rno) rno11973 ENSRNOP00000021862
(RGD:621036)		 P50137
Saccharomyces cerevisiae (Sce) sce378 YBR117C
(S000000321)
Saccharomyces cerevisiae (Sce) sce6529 YPR074C
(S000006278)
Schizosaccharomyces pombe (Spo) spo2508 SPBC2G5.05 Q9URM2
Yarrowia lipolytica (Yli) yli4132 YALI0E06479g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1921669
GO:0005625 soluble fraction C
ISO
MmuMGI:105992
GO:0005634 nucleus C
IDA
SceS000000321
SpoSPBC2G5.05
GO:0005737 cytoplasm C
IDA
SceS000000321
ISS
SceS000006278
SpoSPBC2G5.05
GO:0005777 peroxisome C
ISO
MmuMGI:105992
GO:0005789 endoplasmic reticulum membrane C
ISO
MmuMGI:105992
GO:0005792 microsome C
ISO
MmuMGI:105992
GO:0005811 lipid particle C
IDA
DmeFBgn0037607
GO:0005829 cytosol C
IDA
SpoSPBC2G5.05
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0037607
GO:0009507 chloroplast C
IDA
AthAt2g45290
At3g60750
GO:0009570 chloroplast stroma C
IDA
AthAt3g60750
At2g45290
GO:0009941 chloroplast envelope C
IDA
AthAt3g60750
GO:0000287 magnesium ion binding F
ISO
MmuMGI:105992
GO:0003674 molecular_function F
ND
MmuMGI:1921669
GO:0004802 transketolase activity F
IDA
MmuMGI:105992
IMP
SceS000006278
ISO
MmuMGI:105992
ISS
AthAt3g60750
At2g45290
DmeFBgn0036784
FBgn0037607
SceS000000321
S000006278
SpoSPBC2G5.05
GO:0005529 sugar binding F
ISO
MmuMGI:105992
GO:0030976 thiamin pyrophosphate binding F
ISO
MmuMGI:105992
GO:0048029 monosaccharide binding F
ISO
MmuMGI:105992
GO:0002119 nematode larval development P
IMP
CelWBGene00008506
GO:0006098 pentose-phosphate shunt P
IGI
SceS000000321
IMP
SceS000006278
ISO
MmuMGI:105992
ISS