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Search term: YPR088C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SRP54
SGD link S000006292
Alternative ID YPR088C
Description Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain
Synonyms YPR088C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0780 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Signal recognition particle, subunit Srp54

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g15310 GI:18394225
Arabidopsis thaliana (Ath) At1g48900 GI:11094805
Arabidopsis thaliana (Ath) At2g45770 GI:7484843
Arabidopsis thaliana (Ath) At5g03940 GI:15237580
Arabidopsis thaliana (Ath) At5g49500 GI:15239909
Arabidopsis thaliana (Ath) At5g66970 GI:15240155
Caenorhabditis elegans (Cel) CE09524
(WBGene00009012)		 GI:17539958 Q19639
Drosophila melanogaster (Dme) 7295492
(FBgn0010747)		 GI:17647949 Q9V3D9
Homo sapiens (Hsa) Hs4507215
(SRP54)		 GI:4507215 P61011
Saccharomyces cerevisiae (Sce) YPR088c
(S000006292)		 GI:6325345 P20424
Schizosaccharomyces pombe (Spo) SPCC188.06c GI:19075709 P21565
Encephalitozoon cuniculi (Ecu) ECU04g0980 GI:19074175 Q8SS36
Arabidopsis thaliana (Ath) At1g15310 GI:18394225
Arabidopsis thaliana (Ath) At1g48900 GI:11094805
Arabidopsis thaliana (Ath) At2g45770 GI:7484843
Arabidopsis thaliana (Ath) At5g03940 GI:15237580
Arabidopsis thaliana (Ath) At5g49500 GI:15239909
Arabidopsis thaliana (Ath) At5g66970 GI:15240155
Caenorhabditis elegans (Cel) CE09524
(WBGene00009012)		 GI:17539958 Q19639
Drosophila melanogaster (Dme) 7295492
(FBgn0010747)		 GI:17647949 Q9V3D9
Homo sapiens (Hsa) Hs4507215
(SRP54)		 GI:4507215 P61011
Saccharomyces cerevisiae (Sce) YPR088c
(S000006292)		 GI:6325345 P20424
Schizosaccharomyces pombe (Spo) SPCC188.06c GI:19075709 P21565
Encephalitozoon cuniculi (Ecu) ECU04g0980 GI:19074175 Q8SS36


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaSRP54
GO:0005737 cytoplasm C
IDA
HsaSRP54
ISS
AthAt1g15310
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC188.06c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting		 C
IDA
HsaSRP54
SceS000006292
SpoSPCC188.06c
ISS
AthAt5g03940
At5g66970
At1g15310
At5g49500
At2g45770
At1g48900
DmeFBgn0010747
GO:0005829 cytosol C
IDA
SpoSPCC188.06c
GO:0009507 chloroplast C
IDA
AthAt2g45770
At5g03940
GO:0009534 chloroplast thylakoid C
NAS
AthAt2g45770
GO:0009570 chloroplast stroma C
IDA
AthAt5g03940
GO:0080085 signal recognition particle, chloroplast
targeting		 C
IMP
AthAt5g03940
GO:0003729 mRNA binding F
ISS
AthAt5g49500
At1g48900
At1g15310
At5g03940
GO:0003924 GTPase activity F
IDA
HsaSRP54
IMP
SpoSPCC188.06c
GO:0005048 signal sequence binding F
IDA
AthAt5g03940
IPI
SceS000006292
ISS
DmeFBgn0010747
GO:0005515 protein binding F
IPI
AthAt5g49500
At5g03940
GO:0005525 GTP binding F
IDA
HsaSRP54
ISA
SceS000006292
ISS
AthAt5g66970
At1g15310
At2g45770
At1g48900
At5g49500
At5g03940
GO:0008144 drug binding F
IDA
HsaSRP54
GO:0008312 7S RNA binding F
IDA
HsaSRP54
SceS000006292
IMP
SpoSPCC188.06c
ISS
AthAt5g49500
At1g48900
At1g15310
At5g03940
DmeFBgn0010747
GO:0019003 GDP binding F
IDA
HsaSRP54
GO:0030942 endoplasmic reticulum signal peptide
binding		 F
IDA
HsaSRP54
GO:0043021 ribonucleoprotein binding F
IDA
HsaSRP54
GO:0000003 reproduction P
IMP
CelWBGene00009012
GO:0002119 nematode larval development P
IMP
CelWBGene00009012
GO:0006184 GTP catabolic process P
IMP
SpoSPCC188.06c
GO:0006605 protein targeting P
ISS
AthAt2g45770
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane		 P
IC
HsaSRP54
IMP
SceS000006292
SpoSPCC188.06c
ISS
DmeFBgn0010747
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
ISS
HsaSRP54
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition		 P
IC
SceS000006292
ISA
SceS000006292
ISS
AthAt1g48900
At5g49500
At5g03940
At1g15310
DmeFBgn0010747
HsaSRP54
GO:0007040 lysosome organization P
IMP
DmeFBgn0010747
GO:0009772 photosynthetic electron transport in photosystem
II		 P
IMP
AthAt2g45770
GO:0010027 thylakoid membrane organization P
IMP
AthAt2g45770
GO:0010507 negative regulation of autophagy P
IMP
DmeFBgn0010747
GO:0042493 response to drug P
IDA
HsaSRP54
GO:0045038 protein import into chloroplast thylakoid
membrane		 P
IDA
AthAt5g03940
IMP
AthAt2g45770
GO:0045047 protein targeting to ER P
IMP
HsaSRP54
IPI
SceS000006292

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2362

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SRP54 GI:4507215 P61011
Pan troglodytes (Ptr) SRP54 GI:114652592
Canis familiaris (Cfa) SRP54 GI:50979080
Mus musculus (Mmu) Srp54a GI:31981338
Rattus norvegicus (Rno) Srp54a GI:62899020
Gallus gallus (Gga) SRP54 GI:50748422
Drosophila melanogaster (Dme) Srp54k
(FBgn0010747)		 GI:17647949 Q9V3D9
Anopheles gambiae (Aga) AgaP_AGAP004610 GI:58386979
Caenorhabditis elegans (Cel) F21D5.7
(CE09524;
WBGene00009012)		 GI:17539958 Q19639
Schizosaccharomyces pombe (Spo) srp54
(SPCC188.06c)		 GI:19075709 P21565
Saccharomyces cerevisiae (Sce) SRP54
(S000006292)		 GI:6325345 P20424
Kluyveromyces lactis (Kla) KLLA0D09020g GI:50306973
Eremothecium gossypii (Ego) AGOS_AAR041W GI:45184864
Magnaporthe grisea (Mgr) MGG_05977 GI:39976193
Neurospora crassa (Ncr) NCU09696.1 GI:32419805
Arabidopsis thaliana (Ath) AT1G48900 GI:18402407
Oryza sativa (Osa) Os01g0772800 GI:115440231
Plasmodium falciparum (Pfa) PF14_0477 GI:124809679


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaSRP54
GO:0005737 cytoplasm C
IDA
HsaSRP54
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC188.06c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting		 C
IDA
HsaSRP54
SceS000006292
SpoSPCC188.06c
ISS
AthAt1g48900
DmeFBgn0010747
GO:0005829 cytosol C
IDA
SpoSPCC188.06c
GO:0003729 mRNA binding F
ISS
AthAt1g48900
GO:0003924 GTPase activity F
IDA
HsaSRP54
IMP
SpoSPCC188.06c
GO:0005048 signal sequence binding F
IPI
SceS000006292
ISS
DmeFBgn0010747
PfaPF14_0477
GO:0005525 GTP binding F
IDA
HsaSRP54
ISA
SceS000006292
ISS
AthAt1g48900
GO:0008144 drug binding F
IDA
HsaSRP54
GO:0008312 7S RNA binding F
IDA
HsaSRP54
SceS000006292
IMP
SpoSPCC188.06c
ISS
AthAt1g48900
DmeFBgn0010747
GO:0019003 GDP binding F
IDA
HsaSRP54
GO:0030942 endoplasmic reticulum signal peptide
binding		 F
IDA
HsaSRP54
GO:0043021 ribonucleoprotein binding F
IDA
HsaSRP54
GO:0000003 reproduction P
IMP
CelWBGene00009012
GO:0002119 nematode larval development P
IMP
CelWBGene00009012
GO:0006184 GTP catabolic process P
IMP
SpoSPCC188.06c
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane		 P
IC
HsaSRP54
IMP
SceS000006292
SpoSPCC188.06c
ISS
DmeFBgn0010747
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
ISS
HsaSRP54
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition		 P
IC
SceS000006292
ISA
SceS000006292
ISS
AthAt1g48900
DmeFBgn0010747
HsaSRP54
GO:0007040 lysosome organization P
IMP
DmeFBgn0010747
GO:0010507 negative regulation of autophagy P
IMP
DmeFBgn0010747
GO:0042493 response to drug P
IDA
HsaSRP54
GO:0045047 protein targeting to ER P
IMP
HsaSRP54
IPI
SceS000006292

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_502

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga13658 ENSANGP00000016415
Anopheles gambiae (Aga) aga7172 ENSANGP00000020889
Ashbya gossypii (Ago) ago227 AAR041W
Arabidopsis thaliana (Ath) ath4162 At1g48900.1
Arabidopsis thaliana (Ath) ath22558 At5g03940.1
Caenorhabditis elegans (Cel) cel6912 F21D5.7
(CE09524;
WBGene00009012)
Candida glabrata (Cgl) cgl3865 CAGL0K07986g
Cryptococcus neoformans (Cne) cne3171 167.m03508
Dictyostelium discoideum (Ddi) ddi3918 DDB0167129
Debaryomyces hansenii (Dha) dha4151 DEHA0E20515g
Drosophila melanogaster (Dme) dme8062 CG4659-PA
(FBgn0010747)
Danio rerio (Dre) dre7869 ENSDARP00000004721
(srp54)		 Q7ZVN5
Escherichia coli (Eco) eco2527 16130531
Encephalitozoon cuniculi (Ecu) ecu813 19074175
Takifugu rubripes (Fru) fru14893 SINFRUP00000139972
Takifugu rubripes (Fru) fru14894 SINFRUP00000169403
Takifugu rubripes (Fru) fru14892 SINFRUP00000172834
Gallus gallus (Gga) gga19479 ENSGALP00000016305
Gallus gallus (Gga) gga19477 ENSGALP00000016307
(RCJMB04_4e14)		 Q5F3Y3
Gallus gallus (Gga) gga19478 ENSGALP00000016308
(SRP54)
Homo sapiens (Hsa) hsa9407 ENSP00000216774
(SRP54)		 P61011
Kluyveromyces lactis (Kla) kla2463 KLLA0D09020g
Mus musculus (Mmu) mmu5714 ENSMUSP00000021407
(MGI:1346087)		 P14576-1
Neurospora crassa (Ncr) ncr9440 NCU09696.2
Oryza sativa (Osa) osa26640 3947.m00112
Oryza sativa (Osa) osa32048 4398.m00119
Oryza sativa (Osa) osa48953 5830.m00166
Oryza sativa (Osa) osa86005 8755.m00145
Plasmodium falciparum (Pfa) pfa1157 PF14_0477
Rattus norvegicus (Rno) rno25114 ENSRNOP00000040194
(RGD:621390)		 Q6AYB5
Rattus norvegicus (Rno) rno25115 ENSRNOP00000048945
(RGD:621390)		 Q62801
Saccharomyces cerevisiae (Sce) sce6544 YPR088C
(S000006292)
Schizosaccharomyces pombe (Spo) spo3561 SPCC188.06c P21565
Yarrowia lipolytica (Yli) yli5502 YALI0F03839g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
ISO
MmuMGI:1346087
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC188.06c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting		 C
IDA
SceS000006292
SpoSPCC188.06c
ISS
AthAt5g03940
At1g48900
DmeFBgn0010747
GO:0005829 cytosol C
IDA
SpoSPCC188.06c
GO:0009507 chloroplast C
IDA
AthAt5g03940
GO:0009570 chloroplast stroma C
IDA
AthAt5g03940
GO:0080085 signal recognition particle, chloroplast
targeting		 C
IMP
AthAt5g03940
GO:0003729 mRNA binding F
ISS
AthAt1g48900
At5g03940
GO:0003924 GTPase activity F
IMP
SpoSPCC188.06c
GO:0005048 signal sequence binding F
IDA
AthAt5g03940
IPI
SceS000006292
ISS
DmeFBgn0010747
PfaPF14_0477
GO:0005515 protein binding F
IPI
AthAt5g03940
GO:0005525 GTP binding F
ISA
SceS000006292
ISS
AthAt1g48900
At5g03940
GO:0008312 7S RNA binding F
IDA
SceS000006292
IMP
SpoSPCC188.06c
ISO
MmuMGI:1346087
ISS
AthAt1g48900
At5g03940
DmeFBgn0010747
GO:0043021 ribonucleoprotein binding F
ISO
MmuMGI:1346087
GO:0000003 reproduction P
IMP
CelWBGene00009012
GO:0002119 nematode larval development P
IMP
CelWBGene00009012
GO:0006184 GTP catabolic process P
IMP
SpoSPCC188.06c
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane		 P
IMP
SceS000006292
SpoSPCC188.06c
ISO
MmuMGI:1346087
ISS
DmeFBgn0010747
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition		 P
IC
SceS000006292
ISA
SceS000006292
ISS
AthAt1g48900
At5g03940
DmeFBgn0010747
GO:0007040 lysosome organization P
IMP
DmeFBgn0010747
GO:0010507 negative regulation of autophagy P
IMP
DmeFBgn0010747
GO:0045038 protein import into chloroplast thylakoid
membrane		 P
IDA
AthAt5g03940
GO:0045047 protein targeting to ER P
IPI
SceS000006292

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC188.06c
(P21565)		 YPR088C
(S000006292)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC188.06c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting		 C
IDA
SceS000006292
SpoSPCC188.06c
GO:0005829 cytosol C
IDA
SpoSPCC188.06c
GO:0003924 GTPase activity F
IMP
SpoSPCC188.06c
GO:0005048 signal sequence binding F
IPI
SceS000006292
GO:0005525 GTP binding F
ISA
SceS000006292
GO:0008312 7S RNA binding F
IDA
SceS000006292
IMP
SpoSPCC188.06c
GO:0006184 GTP catabolic process P
IMP
SpoSPCC188.06c
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane		 P
IMP
SceS000006292
SpoSPCC188.06c
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition		 P
IC
SceS000006292
ISA
SceS000006292
GO:0045047 protein targeting to ER P
IPI
SceS000006292

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GO info in one table:

s.khadayate@ucl.ac.uk