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Search term: YPR175W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DPB2
SGD link S000006379
Alternative ID YPR175W
Description Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate
Synonyms YPR175W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3818 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA polymerase epsilon, subunit B

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE07046 GI:17539708
Drosophila melanogaster (Dme) 7295418 GI:7295418 Q9VRQ7
Homo sapiens (Hsa) Hs4505935 GI:4505935
Saccharomyces cerevisiae (Sce) YPR175w
(S000006379)		 GI:6325433
Schizosaccharomyces pombe (Spo) SPBP8B7.14c GI:19113313 O94263


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000006379
SpoSPBP8B7.14c
GO:0005657 replication fork C
TAS
SceS000006379
GO:0005737 cytoplasm C
IDA
SceS000006379
GO:0005829 cytosol C
IDA
SpoSPBP8B7.14c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000006379
ISS
SpoSPBP8B7.14c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBP8B7.14c
GO:0003688 DNA replication origin binding F
IDA
SpoSPBP8B7.14c
GO:0003690 double-stranded DNA binding F
IDA
SceS000006379
GO:0003887 DNA-directed DNA polymerase activity F
IMP
SpoSPBP8B7.14c
TAS
SceS000006379
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPBP8B7.14c
GO:0006272 leading strand elongation P
TAS
SceS000006379
GO:0006273 lagging strand elongation P
TAS
SceS000006379
GO:0006289 nucleotide-excision repair P
TAS
SceS000006379
GO:0006298 mismatch repair P
TAS
SceS000006379
GO:0006342 chromatin silencing P
RCA
SceS000006379
GO:0006348 chromatin silencing at telomere P
RCA
SceS000006379
GO:0016458 gene silencing P
RCA
SceS000006379
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000006379
GO:0045814 negative regulation of gene expression,
epigenetic		 P
RCA
SceS000006379

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101658

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) dpb2
(SPBP8B7.14c)		 GI:19113313 O94263
Saccharomyces cerevisiae (Sce) DPB2
(S000006379)		 GI:37362708
Kluyveromyces lactis (Kla) KLLA0E04697g GI:50308319
Eremothecium gossypii (Ego) AGOS_AEL267C GI:45190339
Magnaporthe grisea (Mgr) MGG_07222 GI:145612579
Neurospora crassa (Ncr) NCU04587.1 GI:32406660


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000006379
SpoSPBP8B7.14c
GO:0005657 replication fork C
TAS
SceS000006379
GO:0005737 cytoplasm C
IDA
SceS000006379
GO:0005829 cytosol C
IDA
SpoSPBP8B7.14c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000006379
ISS
SpoSPBP8B7.14c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBP8B7.14c
GO:0003688 DNA replication origin binding F
IDA
SpoSPBP8B7.14c
GO:0003690 double-stranded DNA binding F
IDA
SceS000006379
GO:0003887 DNA-directed DNA polymerase activity F
IMP
SpoSPBP8B7.14c
TAS
SceS000006379
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPBP8B7.14c
GO:0006272 leading strand elongation P
TAS
SceS000006379
GO:0006273 lagging strand elongation P
TAS
SceS000006379
GO:0006289 nucleotide-excision repair P
TAS
SceS000006379
GO:0006298 mismatch repair P
TAS
SceS000006379
GO:0006342 chromatin silencing P
RCA
SceS000006379
GO:0006348 chromatin silencing at telomere P
RCA
SceS000006379
GO:0016458 gene silencing P
RCA
SceS000006379
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000006379
GO:0045814 negative regulation of gene expression,
epigenetic		 P
RCA
SceS000006379

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2506

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7177 ENSANGP00000021571
Ashbya gossypii (Ago) ago2238 AEL267C
Arabidopsis thaliana (Ath) ath24439 At5g22110.1
Caenorhabditis elegans (Cel) cel5624 F08B4.5
(CE29749;
WBGene00017237)
Candida glabrata (Cgl) cgl2047 CAGL0G09801g
Cryptococcus neoformans (Cne) cne1479 180.m00433
Dictyostelium discoideum (Ddi) ddi12523 DDB0216321
Debaryomyces hansenii (Dha) dha3397 DEHA0E03553g
Drosophila melanogaster (Dme) dme8150 CG10489-PA
(FBgn0035644)
Takifugu rubripes (Fru) fru7631 SINFRUP00000150171
Takifugu rubripes (Fru) fru7630 SINFRUP00000150173
Gallus gallus (Gga) gga20028 ENSGALP00000019955
(POLE2)		 Q5ZKQ6
Gallus gallus (Gga) gga20029 ENSGALP00000019956
(POLE2)
Homo sapiens (Hsa) hsa9487 ENSP00000216367
(POLE2)		 P56282
Kluyveromyces lactis (Kla) kla3160 KLLA0E04697g
Mus musculus (Mmu) mmu5781 ENSMUSP00000021359
(MGI:1197514)		 O54956
Neurospora crassa (Ncr) ncr9864 NCU10155.2
Oryza sativa (Osa) osa17648 3313.m00130
Oryza sativa (Osa) osa32939 4495.m00174
Oryza sativa (Osa) osa61711 6485.m00167
Plasmodium falciparum (Pfa) pfa5114 PFL1655c
Rattus norvegicus (Rno) rno25196 ENSRNOP00000005835
(RGD:1311962)
Saccharomyces cerevisiae (Sce) sce6644 YPR175W
(S000006379)
Schizosaccharomyces pombe (Spo) spo4895 SPBP8B7.14c O94263
Yarrowia lipolytica (Yli) yli6523 YALI0F28215g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000006379
SpoSPBP8B7.14c
ISS
AthAt5g22110
GO:0005657 replication fork C
TAS
SceS000006379
GO:0005737 cytoplasm C
IDA
SceS000006379
GO:0005829 cytosol C
IDA
SpoSPBP8B7.14c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000006379
IPI
AthAt5g22110
ISS
DmeFBgn0035644
SpoSPBP8B7.14c
NAS
DmeFBgn0035644
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBP8B7.14c
GO:0003688 DNA replication origin binding F
IDA
SpoSPBP8B7.14c
GO:0003690 double-stranded DNA binding F
IDA
SceS000006379
GO:0003887 DNA-directed DNA polymerase activity F
IMP
SpoSPBP8B7.14c
ISS
AthAt5g22110
DmeFBgn0035644
TAS
SceS000006379
GO:0000003 reproduction P
IMP
CelWBGene00017237
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00017237
GO:0002119 nematode larval development P
IMP
CelWBGene00017237
GO:0006261 DNA-dependent DNA replication P
NAS
DmeFBgn0035644
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPBP8B7.14c
GO:0006272 leading strand elongation P
TAS
SceS000006379
GO:0006273 lagging strand elongation P
TAS
SceS000006379
GO:0006289 nucleotide-excision repair P
TAS
SceS000006379
GO:0006298 mismatch repair P
TAS
SceS000006379
GO:0006342 chromatin silencing P
RCA
SceS000006379
GO:0006348 chromatin silencing at telomere P
RCA
SceS000006379
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0035644
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017237
GO:0010171 body morphogenesis P
IMP
CelWBGene00017237
GO:0016458 gene silencing P
RCA
SceS000006379
GO:0040007 growth P
IMP
CelWBGene00017237
GO:0040011 locomotion P
IMP
CelWBGene00017237
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000006379
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00017237
GO:0045814 negative regulation of gene expression,
epigenetic		 P
RCA
SceS000006379

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP8B7.14c
(O94263)		 YPR175W
(S000006379)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000006379
SpoSPBP8B7.14c
GO:0005657 replication fork C
TAS
SceS000006379
GO:0005737 cytoplasm C
IDA
SceS000006379
GO:0005829 cytosol C
IDA
SpoSPBP8B7.14c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000006379
ISS
SpoSPBP8B7.14c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBP8B7.14c
GO:0003688 DNA replication origin binding F
IDA
SpoSPBP8B7.14c
GO:0003690 double-stranded DNA binding F
IDA
SceS000006379
GO:0003887 DNA-directed DNA polymerase activity F
IMP
SpoSPBP8B7.14c
TAS
SceS000006379
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPBP8B7.14c
GO:0006272 leading strand elongation P
TAS
SceS000006379
GO:0006273 lagging strand elongation P
TAS
SceS000006379
GO:0006289 nucleotide-excision repair P
TAS
SceS000006379
GO:0006298 mismatch repair P
TAS
SceS000006379
GO:0006342 chromatin silencing P
RCA
SceS000006379
GO:0006348 chromatin silencing at telomere P
RCA
SceS000006379
GO:0016458 gene silencing P
RCA
SceS000006379
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000006379
GO:0045814 negative regulation of gene expression,
epigenetic		 P
RCA
SceS000006379

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk