• Int6 project

    Udagawa T, Nemoto N, Wilkinson CRM, Narashimhan J, Jiang L, Watt S, Zook A, Jones N, Wek RC, Bähler J, Asano K (2008). Int6/eIF3e promotes general translation and Atf1 abundance to modulate Sty1 MAP kinase-dependent stress response in fission yeast. J. Biol. Chem.

    Supplementary data:

    • Expression signal ratios for timecourse experiments of AT treatment in four strain backgrounds. Download data

  • Recombination hotspots

    Ludin K, Mata J, Lehmann E, Bähler J, Kohli J (2008). Global distribution of meiotic recombination hotspots in fission yeast. Chromosoma.

    Supplementary data:

    • Array data from 2 ORF and 4 intergenic arrays (4 repeats). Download data

  • urg1 promototer

    Watt S, Mata J, Lopez-Maury L, Marguerat S, Burns G, Bähler J (2008). urg1: a uracil-regulatable promoter system for fission yeast with short induction and repression times. PLoS ONE 3:e1428

    Supplementary data:

    • Expression signal ratios for Figure 1a and Figure 2.

  • Zinc Response

    Dainty SJ, Kennedy CA, Watt S, Bähler J, Whitehall S (2008). Global role for polyadenylation-assisted nuclear RNA degradation in post-transcriptional gene silencing. Eukaryotic Cell 7:454-464

    Supplementary data:

    • Expression signal ratios of zrt1 mutant vs wild-type strains are given; only data that passed our filtering criteria are shown for two independent biological repeats each. Download data

  • Polyadenylation-assisted nuclear RNA degradation

    Wang S-W, Stevenson AL, Kearsey SE, Watt S, Bähler J (2008). Global role for polyadenylation-assisted nuclear RNA degradation in post-transcriptional gene silencing. Mol Cell Biol 28:656-665

    Supplementary data:

    • Expression signal ratios of mutant vs wild-type strains are given; only data that passed our filtering criteria are shown for two independent biological repeats each with dye swap.Download data

  • Mediator project

    Miklos I, Szilagyi Z, Watt S, Zilahi E, Batta G, Antunovics Z, Enczi K, Bähler J, Sipiczki M (2008). Genomic expression patterns in cell separation mutants of Schizosaccharomyces pombe defective in genes coding for the Mediator subunits Med8/Sep15 and Med31/Sep10.
    Mol Genet Genomics 279:225-238

    Supplementary data:

    • Expression signal ratios of mutant vs wild-type strains are given; only data that passed our filtering criteria are shown for two independent biological repeats each with dye swap.Download data

  • BIOGRID Interaction Database

    Stark C, Breitkreutz B-J, Reguly T, Boucher L, Breitkreutz A, Livstone M, Oughtred R, Lackner DH, Bähler J, Wood V, Dolinski K, Tyers M (2008). The BioGRID interaction database: 2008 update.
    Nucleic Acids Res 36:D637-D640

  • Origin mapping project

    Heichinger C, Penkett CJ, Bähler J, and Nurse P (2006). Genome-wide characterization of fission yeast DNA replication origins.
    EMBO J. 25:5171-5179.

    Complete Data Sets and Supplementary Tables:

    Usually there is one file with normalized data for ORF and Intergenic microarrays for each timepoint and also the self/self (control).

  • Rpb4/RNA polymerase II project

    Sharma N, Marguerat S, Mehta S, Watt S, and Bähler J (2006). The fission yeast Rpb4 subunit of RNA polymerase II plays a specialized role in cell separation.
    Mol. Genet. Genomics 276:545-554.

    Complete Data Sets and Supplementary Tables:


  • Upf1/oxidative stress project

    Rodriguez-Gabriel MA, Watt S, Bähler J, and Russell P (2006). Upf1, an RNA helicase required for nonsense-mediated mRNA Decay, modulates the transcriptional response to oxidative stress in fission yeast.
    Mol. Cell. Biol. 26:6347-6356.

    Complete Data Sets:

    Wild type and upf1 deletion cells during H2O2 treatment: Download data (ftp)


  • AP-1-dependent transcription project

    Jenkins CC, Mata J, Crane RF, Thomas B, Akoulitchev A, Bähler J, and Norbury CJ (2005). Activation of AP-1-dependent transcription by a truncated translation initiation factor.
    Eukaryot. Cell. 4:1840-1850.

    Complete Data Sets:

    int6CT expression and vector controls: Download data (ftp)


  • TFIIH-associated CDK-activating kinase project

    Lee KM, Miklos I, Du H, Watt S, Szilagyi Z, Saiz JE, Madabhushi R, Penkett CJ, Sipiczki M, Bähler J, and Fisher RP (2005). Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast.
    Mol. Biol. Cell 16:2734-2745.

    Complete Data Sets:

    mcs6 temperature-shift experiment (regular normalisation): Download data (ftp)

    pmh1 temperature-shift experiments (regular normalisation): Download data (ftp)

    mcs6 and pmh1 temperature-shift experiments (normalised to external spike controls): Download data (ftp)

    mcs6, pmh1, sep10/med31, and sep15/med8 mutant vs wild-type experiments: Download data (ftp)


  • Zip1/Cadmium project

    Harrison C, Katayama S, Dhut S, Chen D, Jones N, Bähler J, and Toda T (2005). SCFPof1-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast.
    EMBO J. 24:599-610.

    Complete Data Sets:

    One wild-type experiment (0, 15, 60 mins after Cd addition: 3 arrays) and one zip1 experiment (0, 15, 60 mins after Cd addition: 3 arrays):
    Download data (ftp)


  • Silencing/RNAi project

    Hansen KR, Burns G, Mata J, Volpe TA, Martienssen RA, Bähler J, and Thon G. (2005). Global effects on gene expression in fission yeast by silencing and RNA interference machineries.
    Mol. Cell Biol. 25:590-601.

    Complete Data Sets and Supplementary Tables (Tables S1-S10):


  • Telomerase project

    Mandell J, Bähler J, Volpe T, Martienssen R, and Cech T (2005). Global Expression Changes Resulting from Loss of Telomeric DNA in Fission Yeast.
    Genome Biol. 6:R1.

    Complete Data Sets:

    Normalised and processed data:
    Download data (ftp)

    All raw data are available from accession number E-MEXP-201 in ArrayExpress


  • Set9 project

    Sanders SL, Portoso M, Mata J, Bähler J, Allshire RC, and Kouzarides T (2005). Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.
    Cell 119:603-614.

    Complete Data Sets:

    Three independent repeats of set9 mutants vs wild-type cells:
    Download data (ftp)


  • Cisplatin project

    Gatti L, Chen D, Beretta GL, Rustici G, Carenini N, Corna E, Colangelo D, Zunino F, Bähler J, and Perego P (2004). Global gene expression of fission yeast in response to cisplatin.
    Cell. Mol. Life Sci. 61:2253-2263.

    Gene Lists:

    Complete Data Sets:

    Nine cisplatin experiments: wild-type cells exposed to DPP, untreated Pt/R cells, Pt/R cells exposed to DPP, untreated Pt/R cells, 3 independent biological repeats each:
    Download data (ftp)


  • DNA damage project

    Watson A, Mata J, Bähler J, Carr A, and Humphrey T (2004). Genomic expression responses to ionising radiation and the regulatory roles of the Rad3-checkpoint and Sty1 stress-response kinases in fission yeast.
    Mol. Biol. Cell 15:851-860.

    Gene Lists:

    Complete Data Sets:

    Ionising radiation experiments: wild type and five mutants, two timepoints and three biological repeats each; synchronised wild-type experiment, four timepoints with three biological repeats:
    Download data (ftp)


  • Csx1 project

    Rodriguez-Gabriel MA, Burns G, McDonald WH, Martin V, Yates III JR, Bähler J, and Russell P (2003). RNA binding protein Csx1 mediates global control of gene expression in response to oxidative stress.
    EMBO J. 22:6256-6266.

    Complete Data Sets:

    Four stress timecourse experiments: csx1 mutants and wild-type cells exposed to 1 mM H2O2; three timepoints and two biological repeats each:
    Download data (ftp)

    All raw data are available from accession number E-MEXP-176 in ArrayExpress